Blood pressure and Ibuprofen, like Advil and Motrin?

Posted By on August 17, 2022

Doctor Measures Her Blood PressureRead this medical information the other day and thought it likely might be a question many of us may have when taking over the counter (and prescription) doses of the common NSAID Ibuprofen. Check out the full article on GoodRx.

How much does ibuprofen raise your blood pressure?

Studies have looked at how much NSAIDs affect systolic blood pressure (SBP). SBP is the top number when measuring blood pressure. It’s estimated that a person’s SBP will go up by an average of 5 mmHg after taking NSAIDs like ibuprofen.

Other research shows similar results. A review of five studies specifically looked at the effect of ibuprofen on blood pressure. This review found that ibuprofen raised SBP by about 3 to 4 mmHg. The people in these studies took ibuprofen for at least 4 weeks.

A more recent study compared blood pressure changes in over 400 people with RA or OA using NSAIDs for 4 months. Most people were also taking blood pressure medication. Ibuprofen caused a greater rise in blood pressure compared to celecoxib and naproxen (two other NSAIDs). The SBP in people taking ibuprofen rose by about 4 mmHg. In addition, almost 1 in 4 people developed hypertension (chronic high blood pressure) after taking ibuprofen consistently for 4 months.

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